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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TWF1
All Species:
39.09
Human Site:
Y200
Identified Species:
78.18
UniProt:
Q12792
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12792
NP_002813.2
350
40283
Y200
L
N
N
R
Q
L
N
Y
V
Q
L
E
I
D
I
Chimpanzee
Pan troglodytes
XP_001165727
384
43939
Y234
L
N
N
R
Q
L
N
Y
V
Q
L
E
I
D
I
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543726
350
40067
Y200
L
S
N
R
Q
L
N
Y
V
Q
L
E
I
D
I
Cat
Felis silvestris
Mouse
Mus musculus
Q91YR1
350
40061
Y200
L
S
K
K
Q
L
N
Y
V
Q
L
E
I
D
I
Rat
Rattus norvegicus
Q5RJR2
350
40072
Y200
L
S
K
R
Q
L
N
Y
V
Q
L
E
I
D
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508452
357
40765
Y207
L
N
N
K
Q
L
N
Y
V
Q
L
E
V
D
I
Chicken
Gallus gallus
Q5ZM35
349
39817
Y200
L
K
Q
K
K
I
N
Y
I
Q
L
K
L
D
L
Frog
Xenopus laevis
Q68F50
350
40436
Y200
L
R
E
K
R
L
N
Y
V
Q
L
K
I
D
I
Zebra Danio
Brachydanio rerio
Q6GMH3
347
39840
Y198
L
A
E
R
R
I
N
Y
I
Q
L
K
L
D
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VFM9
343
39052
Y200
L
V
R
G
K
H
D
Y
L
Q
F
R
I
D
L
Honey Bee
Apis mellifera
XP_393653
350
39782
Y201
L
G
K
G
I
H
E
Y
V
Q
L
K
I
D
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53250
332
37052
L197
L
D
S
E
G
K
N
L
I
I
F
Q
I
D
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.6
N.A.
97.7
N.A.
94.8
94.5
N.A.
89.9
66.8
79.7
63.1
N.A.
48.2
53.1
N.A.
N.A.
Protein Similarity:
100
90.6
N.A.
99.1
N.A.
97.7
97.4
N.A.
96.3
86.8
91.1
82.5
N.A.
72.2
74
N.A.
N.A.
P-Site Identity:
100
100
N.A.
93.3
N.A.
80
86.6
N.A.
86.6
40
66.6
46.6
N.A.
33.3
46.6
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
93.3
93.3
N.A.
100
86.6
86.6
80
N.A.
60
60
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
0
0
9
0
0
0
0
0
0
100
0
% D
% Glu:
0
0
17
9
0
0
9
0
0
0
0
50
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
17
0
0
0
0
% F
% Gly:
0
9
0
17
9
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
17
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
9
17
0
0
25
9
0
0
75
0
59
% I
% Lys:
0
9
25
34
17
9
0
0
0
0
0
34
0
0
0
% K
% Leu:
100
0
0
0
0
59
0
9
9
0
84
0
17
0
25
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
25
34
0
0
0
84
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% P
% Gln:
0
0
9
0
50
0
0
0
0
92
0
9
0
0
0
% Q
% Arg:
0
9
9
42
17
0
0
0
0
0
0
9
0
0
0
% R
% Ser:
0
25
9
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% T
% Val:
0
9
0
0
0
0
0
0
67
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
92
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _